1N8Z_AB_C

• Mutation(s) in PDB: NA30S, HA91F, YA92W, TA94S, DB102W, YB105F, YB109V
• Mutation(s) cleaned: NA30S,HA91F,YA92W,TA94S,DB102W,YB105F,YB109V
• Location: COR,SUP,COR,COR,RIM,COR,INT
• Hold out type: AB/AG
• Hold out protein(s): AB/AG
• Affinity mutant: 3.8E-10
• Affinity wild-typen: 3.5E-10
• Reference: 12206766
• Protein 1: Herceptin
• Protein 2: erbB-2
• Method: SPR
• Temperaute: 310 K
• Kon mutatant (M^-1s^-1): 2.2E+06
• Kon wild-type (M^-1s^-1): 1E+06
• Koff mutatant (M^-1s^-1): 8.4E-04
• Koff wild-type (M^-1s^-1): 3.5E-04
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None