3BDY_HL_V

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  • Mutation(s) in PDB: DL27aN, PL27cA, RL27dK, SL28T, TL93S, TL94S, KH30S, DH31G, TH53S, NH54E, GH96V, DH98V, RH50A, RH58A
  • Mutation(s) cleaned: DL28N,PL30A,RL31K,SL32T,TL97S,TL98S,KH31S,DH32G,TH55S,NH56E,GH101V,DH103V,RH51A,RH60A
  • Location: SUR,SUR,RIM,RIM,COR,COR,SUR,SUR,SUR,RIM,SUR,RIM,SUP,SUR
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG
  • Affinity mutant: 3E-09
  • Affinity wild-typen: 3E-07
  • Reference: 21526167
  • Protein 1: bH1 Fab
  • Protein 2: VEGF
  • Method: SPR
  • Temperaute: 303 K
  • Kon mutatant (M-1s-1): 3.5E+05
  • Kon wild-type (M-1s-1): 3.3E+04
  • Koff mutatant (M-1s-1): 1E-03
  • Koff wild-type (M-1s-1): 9.9E-03
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None