SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3BDY_HL_V
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- Mutation(s) in PDB:
DL27aN,
PL27cA,
RL27dK,
SL28T,
TL93S,
TL94S,
KH30S,
DH31G,
TH53S,
NH54E,
GH96V,
DH98V,
RH50A,
RH58A
- Mutation(s) cleaned: DL28N,PL30A,RL31K,SL32T,TL97S,TL98S,KH31S,DH32G,TH55S,NH56E,GH101V,DH103V,RH51A,RH60A
- Location: SUR,SUR,RIM,RIM,COR,COR,SUR,SUR,SUR,RIM,SUR,RIM,SUP,SUR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 3E-09
- Affinity wild-typen: 3E-07
- Reference: 21526167
- Protein 1: bH1 Fab
- Protein 2: VEGF
- Method: SPR
- Temperaute: 303 K
- Kon mutatant (M-1s-1): 3.5E+05
- Kon wild-type (M-1s-1): 3.3E+04
- Koff mutatant (M-1s-1): 1E-03
- Koff wild-type (M-1s-1): 9.9E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None