3BE1_HL_A

 Back    Reset view

  • Mutation(s) in PDB: DL27aN, PL27cA, RL27dK, SL28T, TL93S, TL94S, KH30S, DH31G, TH53S, NH54E, GH96V, DH98V, YL32A
  • Mutation(s) cleaned: DL28N,PL30A,RL31K,SL32T,TL97S,TL98S,KH30S,DH31G,TH54S,NH55E,GH100V,DH102V,YL36A
  • Location: SUR,SUR,RIM,RIM,RIM,COR,SUR,SUR,SUR,SUR,INT,RIM,COR
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG
  • Affinity mutant: 1E-10
  • Affinity wild-typen: 2E-08
  • Reference: 21526167
  • Protein 1: bH1 Fab
  • Protein 2: erbB-2
  • Method: SPR
  • Temperaute: 303 K
  • Kon mutatant (M-1s-1): 6.2E+05
  • Kon wild-type (M-1s-1): 1E+05
  • Koff mutatant (M-1s-1): 4E-05
  • Koff wild-type (M-1s-1): 2.1E-03
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None