SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3BE1_HL_A
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- Mutation(s) in PDB:
DL27aN,
PL27cA,
RL27dK,
SL28T,
TL93S,
TL94S,
KH30S,
DH31G,
TH53S,
NH54E,
GH96V,
DH98V,
YL32A
- Mutation(s) cleaned: DL28N,PL30A,RL31K,SL32T,TL97S,TL98S,KH30S,DH31G,TH54S,NH55E,GH100V,DH102V,YL36A
- Location: SUR,SUR,RIM,RIM,RIM,COR,SUR,SUR,SUR,SUR,INT,RIM,COR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 1E-10
- Affinity wild-typen: 2E-08
- Reference: 21526167
- Protein 1: bH1 Fab
- Protein 2: erbB-2
- Method: SPR
- Temperaute: 303 K
- Kon mutatant (M-1s-1): 6.2E+05
- Kon wild-type (M-1s-1): 1E+05
- Koff mutatant (M-1s-1): 4E-05
- Koff wild-type (M-1s-1): 2.1E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None