2NY7_HL_G

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  • Mutation(s) in PDB: KG231C, EG268C, WG95M, MG433A, CG96W, CG275V, CG109I, CG428Q
  • Mutation(s) cleaned: KG66C,EG103C,WG13M,MG231A,CG14W,CG110V,CG27I,CG226Q
  • Location: SUR,SUR,INT,INT,SUR,SUR,SUR,SUR
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG,1GC1_G_C
  • Affinity mutant: 6.04E-08
  • Affinity wild-typen: 3.64E-08
  • Reference: 17301785
  • Protein 1: b12 fab
  • Protein 2: gp120
  • Method: SPR
  • Temperaute: 298(assumed) K
  • Kon mutatant (M-1s-1): 2.22E+05
  • Kon wild-type (M-1s-1): 5.61E+04
  • Koff mutatant (M-1s-1): 1.34E-02
  • Koff wild-type (M-1s-1): 2.04E-03
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None