SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2NY7_HL_G
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- Mutation(s) in PDB:
KG231C,
EG267C,
CG109I,
CG428Q
- Mutation(s) cleaned: KG66C,EG102C,CG27I,CG226Q
- Location: SUR,SUR,SUR,SUR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG,1GC1_G_C
- Affinity mutant: 3.9E-08
- Affinity wild-typen: 3.64E-08
- Reference: 17301785
- Protein 1: b12 fab
- Protein 2: gp120
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 1.72E+05
- Kon wild-type (M-1s-1): 5.61E+04
- Koff mutatant (M-1s-1): 6.7E-03
- Koff wild-type (M-1s-1): 2.04E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None