SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3IDX_HL_G
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- Mutation(s) in PDB:
WG95M,
MG433A,
CG96W,
CG275V
- Mutation(s) cleaned: WG13M,MG247A,CG14W,CG129V
- Location: INT,SUR,SUR,SUR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG,1GC1_G_C
- Affinity mutant: 9.75E-08
- Affinity wild-typen: 2.91E-07
- Reference: 17301785
- Protein 1: b13 fab
- Protein 2: gp120
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 9.96E+03
- Kon wild-type (M-1s-1): 4.75E+03
- Koff mutatant (M-1s-1): 9.71E-04
- Koff wild-type (M-1s-1): 1.38E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None