3MZW_A_B

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  • Mutation(s) in PDB: NB23T, NB43E, AB54S
  • Mutation(s) cleaned: NB18T,NB38E,AB49S
  • Location: SUR,SUR,SUR
  • Hold out type:
  • Hold out protein(s): 3MZW_A_B,1FC2_C_D,3N85_A_LH
  • Affinity mutant: 2.9E-11
  • Affinity wild-typen: 2.3E-11
  • Reference: 20226194
  • Protein 1: Affibody ZHER2:342
  • Protein 2: erbB-2
  • Method: SPR
  • Temperaute: 298(assumed) K
  • Kon mutatant (M-1s-1): 3.9E+06
  • Kon wild-type (M-1s-1): 4E+06
  • Koff mutatant (M-1s-1): 1.1E-04
  • Koff wild-type (M-1s-1): 8.8E-05
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None