SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3MZW_A_B
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- Mutation(s) in PDB:
NB23T,
AB42S,
AB46S,
LB51T
- Mutation(s) cleaned: NB18T,AB37S,AB41S,LB46T
- Location: SUR,SUR,SUR,SUR
- Hold out type:
- Hold out protein(s): 3MZW_A_B,1FC2_C_D,3N85_A_LH
- Affinity mutant: 1.8E-11
- Affinity wild-typen: 2.3E-11
- Reference: 20226194
- Protein 1: Affibody ZHER2:342
- Protein 2: erbB-2
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 4.6E+06
- Kon wild-type (M-1s-1): 4E+06
- Koff mutatant (M-1s-1): 7E-05
- Koff wild-type (M-1s-1): 8.8E-05
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None