3NGB_HL_G

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  • Mutation(s) in PDB: TH33Y, GH55S, AH56G, VH57T, PH62K, VH73T, YH74S
  • Mutation(s) cleaned: TH33Y,GH56S,AH57G,VH58T,PH63K,VH74T,YH75S
  • Location: SUP,SUP,COR,COR,RIM,COR,RIM
  • Hold out type: AB/AG
  • Hold out protein(s): AB/AG
  • Affinity mutant: 1.52E-07
  • Affinity wild-typen: 5.76E-09
  • Reference: 20616231
  • Protein 1: VRC01 fab
  • Protein 2: gp120
  • Method: SPR
  • Temperaute: 298 K
  • Kon mutatant (M-1s-1): 3.732E+03
  • Kon wild-type (M-1s-1): 3.83E+04
  • Koff mutatant (M-1s-1): 5.67E-04
  • Koff wild-type (M-1s-1): 2.2E-04
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None