3NGB_HL_G

• Mutation(s) in PDB: IH30T, KH52N, RH53N, GH54S, AH56G, VH57T, RH61Q, PH62K, VH73T, YH74S, YL28S
• Mutation(s) cleaned: IH30T,KH52N,RH54N,GH55S,AH57G,VH58T,RH62Q,PH63K,VH74T,YH75S,YL26S
• Location: COR,COR,RIM,COR,COR,COR,COR,RIM,COR,RIM,RIM
• Hold out type: AB/AG
• Hold out protein(s): AB/AG
• Affinity mutant: 2.47E-08
• Affinity wild-typen: 5.76E-09
• Reference: 20616231
• Protein 1: VRC01 fab
• Protein 2: gp120
• Method: SPR
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): 6.32E+03
• Kon wild-type (M^-1s^-1): 3.83E+04
• Koff mutatant (M^-1s^-1): 1.56E-04
• Koff wild-type (M^-1s^-1): 2.2E-04
• ΔH mutant (kcal mol^-1)): None
• ΔH wild-type (kcal mol^-1)): None
• ΔS mutant (cal mol^-1 K^-1): None
• ΔS wild-type (cal mol^-1 K^-1): None