SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
3NGB_HL_G
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- Mutation(s) in PDB:
CH32S,
CH98A
- Mutation(s) cleaned: CH32S,CH102A
- Location: INT,SUR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 8.92E-09
- Affinity wild-typen: 5.76E-09
- Reference: 20616231
- Protein 1: VRC01 fab
- Protein 2: gp120
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 3.87E+04
- Kon wild-type (M-1s-1): 3.83E+04
- Koff mutatant (M-1s-1): 3.45E-04
- Koff wild-type (M-1s-1): 2.2E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None