SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1KIP_AB_C
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- Mutation(s) in PDB:
AB32Y
- Mutation(s) cleaned: AB32Y
- Location: SUP
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 3.7E-09
- Affinity wild-typen: 1.43E-08
- Reference: 8952503
- Protein 1: IgG1-kappa D1.3 Fv
- Protein 2: HEW Lysozyme
- Method: ITC
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -21.5
- ΔH wild-type (kcal mol-1)): -17.2
- ΔS mutant (cal mol-1 K-1): -33.7
- ΔS wild-type (cal mol-1 K-1): -22.2