SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1E50_A_B
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- Mutation(s) in PDB:
NA109A
- Mutation(s) cleaned: NA51A
- Location: SUP
- Hold out type:
- Hold out protein(s): 1E50_A_B,1H9D_A_B
- Affinity mutant: 2.81E-07
- Affinity wild-typen: 2.61E-08
- Reference: 11257229
- Protein 1: AML1 Runx1 Runt domain
- Protein 2: Core-binding factor beta
- Method: ESMA
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None