SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2DSQ_I_G
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- Mutation(s) in PDB:
RI56A
- Mutation(s) cleaned: RI41A
- Location: INT
- Hold out type:
- Hold out protein(s): 2DSQ_I_G
- Affinity mutant: 4.81E-10
- Affinity wild-typen: 4.14E-10
- Reference: 9733769
- Protein 1: IGF-I
- Protein 2: IGFBP1
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 6.84E+05
- Kon wild-type (M-1s-1): 6.71E+05
- Koff mutatant (M-1s-1): 3.29E-04
- Koff wild-type (M-1s-1): 2.78E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None