SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1WQJ_I_B
Back
Reset view
- Mutation(s) in PDB:
RI36A,
RI37A
- Mutation(s) cleaned: RI35A,RI36A
- Location: SUR,INT
- Hold out type:
- Hold out protein(s): 1WQJ_I_B
- Affinity mutant: 3.28E-08
- Affinity wild-typen: 5.78E-09
- Reference: 9733769
- Protein 1: IGF-I
- Protein 2: IGF-1R
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 1.64E+05
- Kon wild-type (M-1s-1): 4.83E+05
- Koff mutatant (M-1s-1): 5.38E-03
- Koff wild-type (M-1s-1): 2.79E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None