SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4HSA_AB_C
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- Mutation(s) in PDB:
WA67V
- Mutation(s) cleaned: WA40V
- Location: SUR
- Hold out type:
- Hold out protein(s): 4HSA_AB_C
- Affinity mutant: 1.69E-09
- Affinity wild-typen: 2.46E-09
- Reference: 23695682
- Protein 1: Interleukin-17a
- Protein 2: Interleukin-17 receptor A
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 2.91E+05
- Kon wild-type (M-1s-1): 2.46E+05
- Koff mutatant (M-1s-1): 4.9E-04
- Koff wild-type (M-1s-1): 3.2E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None