4JEU_A_B

• Mutation(s) in PDB: LB165A, EB166A
• Mutation(s) cleaned: LB147A,EB148A
• Location: INT,COR
• Hold out type:
• Hold out protein(s): 4JEU_A_B
• Affinity mutant: 7.7E-09
• Affinity wild-typen: 1.4E-09
• Reference: 18337752
• Protein 1: Munc18a
• Protein 2: Syntaxin-1A
• Method: ITC
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): -
• Kon wild-type (M^-1s^-1): -
• Koff mutatant (M^-1s^-1): -
• Koff wild-type (M^-1s^-1): -
• ΔH mutant (kcal mol^-1)): -34.8
• ΔH wild-type (kcal mol^-1)): -34.6
• ΔS mutant (cal mol^-1 K^-1): -79.6534546935
• ΔS wild-type (cal mol^-1 K^-1): -75.5946284933