SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4KRL_A_B
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- Mutation(s) in PDB:
DA355T,
FA357A
- Mutation(s) cleaned: DA49T,FA51A
- Location: COR,RIM
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: >5E-06
- Affinity wild-typen: 2.19E-07
- Reference: 23791944
- Protein 1: Epidermal growth factor receptor
- Protein 2: Nanobody 7D12
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None