SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2C5D_AB_CD
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- Mutation(s) in PDB:
LA620A,
LB620A
- Mutation(s) cleaned: LA324A,LB324A
- Location: INT,INT
- Hold out type:
- Hold out protein(s): 2C5D_A_C,4RA0_A_C,2C5D_AB_CD
- Affinity mutant: 1.24E-07
- Affinity wild-typen: 4E-09
- Reference: 12218057
- Protein 1: GAS6
- Protein 2: Axl
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 1.5E+03
- Kon wild-type (M-1s-1): 3.8E+04
- Koff mutatant (M-1s-1): 1.5E-04
- Koff wild-type (M-1s-1): 1.5E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None