SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
5C6T_HL_A
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- Mutation(s) in PDB:
YA280A,
NA293A,
DA295A
- Mutation(s) cleaned: YA182A,NA195A,DA197A
- Location: SUP,RIM,RIM
- Hold out type: AB/AG
- Hold out protein(s): AB/AG
- Affinity mutant: 1.87E-08
- Affinity wild-typen: 1.3E-10
- Reference: 26365435
- Protein 1: 1G2 fab
- Protein 2: HCMV glycoprotein B
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 2.1E+04
- Kon wild-type (M-1s-1): 2.95E+05
- Koff mutatant (M-1s-1): 3.917E-04
- Koff wild-type (M-1s-1): 3.75E-05
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None