SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4NKQ_C_AB
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- Mutation(s) in PDB:
YB224A,
QB225A,
KB226A,
LB227A,
SB228A,
YB229A
- Mutation(s) cleaned: YB119A,QB120A,KB121A,LB122A,SB123A,YB124A
- Location: SUR,SUR,SUR,SUR,SUR,SUR
- Hold out type:
- Hold out protein(s): 4NKQ_C_AB,4RS1_A_B
- Affinity mutant: 2.9E-10
- Affinity wild-typen: 4.9E-10
- Reference: 27396825
- Protein 1: GM-CSF
- Protein 2: GMR alpha . cytokine receptor common subunit beta
- Method: RA
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None