SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1U7F_B_AC
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- Mutation(s) in PDB:
RB378A
- Mutation(s) cleaned: RB65A
- Location: RIM
- Hold out type:
- Hold out protein(s): 1U7F_B_AC
- Affinity mutant: 1.09E-06
- Affinity wild-typen: 5.8E-08
- Reference: 15350224
- Protein 1: Smad4
- Protein 2: Smad3
- Method: ITC
- Temperaute: 310 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -8.5
- ΔH wild-type (kcal mol-1)): -7.5
- ΔS mutant (cal mol-1 K-1): 0.01
- ΔS wild-type (cal mol-1 K-1): 8.8