1U7F_B_AC

• Mutation(s) in PDB: DB493A
• Mutation(s) cleaned: DB140A
• Location: COR
• Hold out type:
• Hold out protein(s): 1U7F_B_AC
• Affinity mutant: 5.29E-06
• Affinity wild-typen: 5.8E-08
• Reference: 15350224
• Protein 1: Smad4
• Protein 2: Smad3
• Method: ITC
• Temperaute: 310 K
• Kon mutatant (M^-1s^-1): -
• Kon wild-type (M^-1s^-1): -
• Koff mutatant (M^-1s^-1): -
• Koff wild-type (M^-1s^-1): -
• ΔH mutant (kcal mol^-1)): -3.8
• ΔH wild-type (kcal mol^-1)): -7.5
• ΔS mutant (cal mol^-1 K^-1): 11.9
• ΔS wild-type (cal mol^-1 K^-1): 8.8