SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2REX_A_B
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- Mutation(s) in PDB:
LA1815Y
- Mutation(s) cleaned: LA70Y
- Location: COR
- Hold out type:
- Hold out protein(s): 2REX_A_B,3Q3J_A_B,3EG5_A_B
- Affinity mutant: 1.41E-05
- Affinity wild-typen: 5.5E-06
- Reference: 21610070
- Protein 1: Plexin-B1
- Protein 2: Rnd-1
- Method: ITC
- Temperaute: 298 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -1.4
- ΔH wild-type (kcal mol-1)): -6.7
- ΔS mutant (cal mol-1 K-1): 17.4
- ΔS wild-type (cal mol-1 K-1): 1.68