SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1JTG_A_B
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- Mutation(s) in PDB:
DB49A
- Mutation(s) cleaned: DB49A
- Location: COR
- Hold out type:
- Hold out protein(s): 1XXM_A_C,1S0W_A_C,1JTG_A_B,2G2U_A_B,2G2W_A_B,3N4I_A_B,1JTD_A_B,3QHY_A_B
- Affinity mutant: 1.96E-08
- Affinity wild-typen: 1.11E-10
- Reference: 17430899
- Protein 1: TEM-1 beta-lactamase
- Protein 2: BLIP
- Method: ITC
- Temperaute: 283 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): 7.8
- ΔH wild-type (kcal mol-1)): -7.4
- ΔS mutant (cal mol-1 K-1): 63.0
- ΔS wild-type (cal mol-1 K-1): 21.1