SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2C0L_A_B
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- Mutation(s) in PDB:
QA586R
- Mutation(s) cleaned: QA239R
- Location: INT
- Hold out type:
- Hold out protein(s): 2C0L_A_B,3R9A_AC_B
- Affinity mutant: 1.34E-06
- Affinity wild-typen: 1.09E-07
- Reference: 17157249
- Protein 1: TRP region of PEX5
- Protein 2: Sterol carrier protein 2
- Method: ITC
- Temperaute: 305 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -4.16
- ΔH wild-type (kcal mol-1)): -10.1
- ΔS mutant (cal mol-1 K-1): 13.4
- ΔS wild-type (cal mol-1 K-1): -0.962