4G0N_A_B

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  • Mutation(s) in PDB: NB64A
  • Mutation(s) cleaned: NB11A
  • Location: RIM
  • Hold out type:
  • Hold out protein(s): 4G0N_A_B,3KUD_A_B,1LFD_A_B,1GUA_A_B,1C1Y_A_B,1K8R_A_B,1HE8_A_B,1E96_A_B
  • Affinity mutant: 9.45E-08
  • Affinity wild-typen: 8.02E-08
  • Reference: 15236966
  • Protein 1: H-Ras1
  • Protein 2: Raf-RBD
  • Method: ITC
  • Temperaute: 308 K
  • Kon mutatant (M-1s-1): -
  • Kon wild-type (M-1s-1): -
  • Koff mutatant (M-1s-1): -
  • Koff wild-type (M-1s-1): -
  • ΔH mutant (kcal mol-1)): -7.6
  • ΔH wild-type (kcal mol-1)): -8.6
  • ΔS mutant (cal mol-1 K-1): 7.4675324675
  • ΔS wild-type (cal mol-1 K-1): 4.55