SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2AJF_A_E
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- Mutation(s) in PDB:
FE360S
- Mutation(s) cleaned: FE38S
- Location: SUR
- Hold out type:
- Hold out protein(s): 2AJF_A_E
- Affinity mutant: 1.41E-08
- Affinity wild-typen: 1.62E-08
- Reference: 15791205
- Protein 1: Human Angiotensin-converting enzyme 2
- Protein 2: SARS spike protein receptor binding domain
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 6.23E+04
- Kon wild-type (M-1s-1): 7.12E+04
- Koff mutatant (M-1s-1): 8.8E-04
- Koff wild-type (M-1s-1): 1.16E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None