SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
4G0N_A_B
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- Mutation(s) in PDB:
FB61W,
NB71R,
VB88I
- Mutation(s) cleaned: FB8W,NB18R,VB35I
- Location: SUR,RIM,COR
- Hold out type:
- Hold out protein(s): 4G0N_A_B,3KUD_A_B,1LFD_A_B,1GUA_A_B,1C1Y_A_B,1K8R_A_B,1HE8_A_B,1E96_A_B
- Affinity mutant: 2.4E-07
- Affinity wild-typen: 1.3E-07
- Reference: 20361980
- Protein 1: H-Ras1
- Protein 2: Raf-RBD
- Method: IAFL
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None