SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1IAR_A_B
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- Mutation(s) in PDB:
IA5R
- Mutation(s) cleaned: IA5R
- Location: COR
- Hold out type:
- Hold out protein(s): 1IAR_A_B
- Affinity mutant: 6.21E-10
- Affinity wild-typen: 1.62E-10
- Reference: 9050834
- Protein 1: Interleukin-4
- Protein 2: Interleukin-4 receptor
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 1.4E+07
- Kon wild-type (M-1s-1): 1.3E+07
- Koff mutatant (M-1s-1): 8.7E-03
- Koff wild-type (M-1s-1): 2.1E-03
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None