SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1JTD_A_B
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- Mutation(s) in PDB:
NB112A
- Mutation(s) cleaned: NB74A
- Location: SUP
- Hold out type:
- Hold out protein(s): 1JTD_A_B,1XXM_A_C,1S0W_A_C,1JTG_A_B,3QHY_A_B,2G2U_A_B,2G2W_A_B,3N4I_A_B
- Affinity mutant: 3.7E-12
- Affinity wild-typen: 4.8E-13
- Reference: 23625930
- Protein 1: TEM-1 beta-lactamase
- Protein 2: BLIP-II
- Method: IASP
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 5.4E+06
- Kon wild-type (M-1s-1): 7.7E+06
- Koff mutatant (M-1s-1): 2.01E-05
- Koff wild-type (M-1s-1): 3.7E-06
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None