SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1YCS_A_B
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- Mutation(s) in PDB:
MA133L,
VA203A,
NA239Y,
NA268D,
FA270L
- Mutation(s) cleaned: MA37L,VA107A,NA143Y,NA172D,FA174L
- Location: INT,INT,COR,INT,INT
- Hold out type:
- Hold out protein(s): 1YCS_A_B
- Affinity mutant: 1.6E-06
- Affinity wild-typen: 2.2E-06
- Reference: 16887812
- Protein 1: p53 core domain
- Protein 2: 53BP2
- Method: ITC
- Temperaute: 293 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None