3EG5_A_B

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  • Mutation(s) in PDB: TB164N, SB165N, HB166N
  • Mutation(s) cleaned: TB73N,SB74N,HB75N
  • Location: COR,COR,SUP
  • Hold out type:
  • Hold out protein(s): 3EG5_A_B,1GRN_A_B,2REX_A_B,3Q3J_A_B
  • Affinity mutant: 7.4E-06
  • Affinity wild-typen: 1.25E-06
  • Reference: 18829452
  • Protein 1: M. musculus Cdc42
  • Protein 2: MdiaN-TSH
  • Method: ITC
  • Temperaute: 293 K
  • Kon mutatant (M-1s-1): -
  • Kon wild-type (M-1s-1): -
  • Koff mutatant (M-1s-1): -
  • Koff wild-type (M-1s-1): -
  • ΔH mutant (kcal mol-1)): 2.2
  • ΔH wild-type (kcal mol-1)): 3.28
  • ΔS mutant (cal mol-1 K-1): 31.023890785
  • ΔS wild-type (cal mol-1 K-1): 38.2252559727