SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
5XCO_A_B
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- Mutation(s) in PDB:
DA12C
- Mutation(s) cleaned: DA13C
- Location: SUR
- Hold out type:
- Hold out protein(s): 5XCO_A_B,5TAR_A_B,2A9K_A_B
- Affinity mutant: 3.5E-08
- Affinity wild-typen: 8.9E-09
- Reference: 28740607
- Protein 1: K-Ras
- Protein 2: KRpep-2d
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 1E+06
- Kon wild-type (M-1s-1): 1.3E+06
- Koff mutatant (M-1s-1): 3.5E-02
- Koff wild-type (M-1s-1): 1.1E-02
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None