5XCO_A_B

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  • Mutation(s) in PDB: DA12G
  • Mutation(s) cleaned: DA13G
  • Location: SUR
  • Hold out type:
  • Hold out protein(s): 5XCO_A_B,5TAR_A_B,2A9K_A_B
  • Affinity mutant: 5.8E-08
  • Affinity wild-typen: 8.9E-09
  • Reference: 28740607
  • Protein 1: K-Ras
  • Protein 2: KRpep-2d
  • Method: SPR
  • Temperaute: 298(assumed) K
  • Kon mutatant (M-1s-1): 1.6E+06
  • Kon wild-type (M-1s-1): 1.3E+06
  • Koff mutatant (M-1s-1): 9.3E-02
  • Koff wild-type (M-1s-1): 1.1E-02
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None