1MQ8_A_B

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  • Mutation(s) in PDB: CB161L, CB299F, LB289C, KB294C
  • Mutation(s) cleaned: CB32L,CB170F,LB160C,KB165C
  • Location: INT,INT,SUR,SUR
  • Hold out type:
  • Hold out protein(s): 1MQ8_A_B
  • Affinity mutant: 1.6E-03
  • Affinity wild-typen: 3E-06
  • Reference: 12526797
  • Protein 1: Intercellular adhesion molecule I
  • Protein 2: Integrin alpha-L
  • Method: SPR
  • Temperaute: 298 K
  • Kon mutatant (M-1s-1): 2.3E+03
  • Kon wild-type (M-1s-1): 1.33E+05
  • Koff mutatant (M-1s-1): 3.6E+00
  • Koff wild-type (M-1s-1): 4.3E-01
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None