SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1MQ8_A_B
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- Mutation(s) in PDB:
CB299F,
TB300C
- Mutation(s) cleaned: CB170F,TB171C
- Location: INT,SUR
- Hold out type:
- Hold out protein(s): 1MQ8_A_B
- Affinity mutant: 9.4E-06
- Affinity wild-typen: 3E-06
- Reference: 12526797
- Protein 1: Intercellular adhesion molecule I
- Protein 2: Integrin alpha-L
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 8.9E+04
- Kon wild-type (M-1s-1): 1.33E+05
- Koff mutatant (M-1s-1): 7.6E-01
- Koff wild-type (M-1s-1): 4.3E-01
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None