2KSO_A_B

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  • Mutation(s) in PDB: RA56E, HB47E
  • Mutation(s) cleaned: RA43E,HB20E
  • Location: RIM,RIM
  • Hold out type:
  • Hold out protein(s): 2KSO_A_B
  • Affinity mutant: 1.12E-05
  • Affinity wild-typen: 5.2E-06
  • Reference: 22244754
  • Protein 1: Ephrin type-A receptor 2 SAM
  • Protein 2: SHIP2 SAM
  • Method: ITC
  • Temperaute: 298(assumed) K
  • Kon mutatant (M-1s-1): -
  • Kon wild-type (M-1s-1): -
  • Koff mutatant (M-1s-1): -
  • Koff wild-type (M-1s-1): -
  • ΔH mutant (kcal mol-1)): -7.5
  • ΔH wild-type (kcal mol-1)): -2.5
  • ΔS mutant (cal mol-1 K-1): -2.6845637584
  • ΔS wild-type (cal mol-1 K-1): 15.7718120805