SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2KSO_A_B
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- Mutation(s) in PDB:
RA56E,
HB47E
- Mutation(s) cleaned: RA43E,HB20E
- Location: RIM,RIM
- Hold out type:
- Hold out protein(s): 2KSO_A_B
- Affinity mutant: 1.12E-05
- Affinity wild-typen: 5.2E-06
- Reference: 22244754
- Protein 1: Ephrin type-A receptor 2 SAM
- Protein 2: SHIP2 SAM
- Method: ITC
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -7.5
- ΔH wild-type (kcal mol-1)): -2.5
- ΔS mutant (cal mol-1 K-1): -2.6845637584
- ΔS wild-type (cal mol-1 K-1): 15.7718120805