SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1YQV_HL_Y
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- Mutation(s) in PDB:
RY68K,
TY40S,
IY55V,
SY91T,
QY121H
- Mutation(s) cleaned: RY68K,TY40S,IY55V,SY91T,QY121H
- Location: COR,INT,INT,INT,SUR
- Hold out type: AB/AG
- Hold out protein(s): AB/AG,1UUZ_A_D
- Affinity mutant: 4.45E-12
- Affinity wild-typen: 3.72E-12
- Reference: 9252107
- Protein 1: HyHEL-5 fab
- Protein 2: HEW Lysozyme
- Method: ITC
- Temperaute: 283 K
- Kon mutatant (M-1s-1): -
- Kon wild-type (M-1s-1): -
- Koff mutatant (M-1s-1): -
- Koff wild-type (M-1s-1): -
- ΔH mutant (kcal mol-1)): -15.5
- ΔH wild-type (kcal mol-1)): -18.7
- ΔS mutant (cal mol-1 K-1): -2.8268551237
- ΔS wild-type (cal mol-1 K-1): -13.7809187279