1LFD_A_B

• Mutation(s) in PDB: SA22K
• Mutation(s) cleaned: SA9K
• Location: INT
• Hold out type:
• Hold out protein(s): 1LFD_A_B,4G0N_A_B,3KUD_A_B,1K8R_A_B,1HE8_A_B,1GUA_A_B,1C1Y_A_B
• Affinity mutant: 5.24E-06
• Affinity wild-typen: 1.15E-06
• Reference: 15197281
• Protein 1: RalGDS-RBD
• Protein 2: H-Ras1
• Method: ITC
• Temperaute: 298 K
• Kon mutatant (M^-1s^-1): -
• Kon wild-type (M^-1s^-1): -
• Koff mutatant (M^-1s^-1): -
• Koff wild-type (M^-1s^-1): -
• ΔH mutant (kcal mol^-1)): -14.0
• ΔH wild-type (kcal mol^-1)): -11.2
• ΔS mutant (cal mol^-1 K^-1): -22.8
• ΔS wild-type (cal mol^-1 K^-1): -10.4