SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1KTZ_A_B
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- Mutation(s) in PDB:
VA92I
- Mutation(s) cleaned: VA62I
- Location: COR
- Hold out type:
- Hold out protein(s): 1KTZ_A_B,1REW_AB_C,2QJ9_AB_C,2QJA_AB_C,2QJB_AB_C,3B4V_AB_C
- Affinity mutant: 1.1E-07
- Affinity wild-typen: 7.3E-08
- Reference: 19161338
- Protein 1: Transforming growth factor beta 3
- Protein 2: TGF-beta type II receptor
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 7E+05
- Kon wild-type (M-1s-1): 7.4E+05
- Koff mutatant (M-1s-1): 7.2E-02
- Koff wild-type (M-1s-1): 5.4E-02
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None