SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
1REW_AB_C
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- Mutation(s) in PDB:
AA34D,
DA53A,
AB34D,
DB53A
- Mutation(s) cleaned: AA23D,DA42A,AB23D,DB42A
- Location: SUR,COR,SUR,SUR
- Hold out type:
- Hold out protein(s): 1REW_AB_C,2QJ9_AB_C,2QJA_AB_C,2QJB_AB_C,1KTZ_A_B
- Affinity mutant: 4.89E-10
- Affinity wild-typen: 6.67E-10
- Reference: 10880444
- Protein 1: Bone morphogenetic protein-2
- Protein 2: BMPR-IA receptor
- Method: SPR
- Temperaute: 298 K
- Kon mutatant (M-1s-1): 9E+05
- Kon wild-type (M-1s-1): 6E+05
- Koff mutatant (M-1s-1): 4.4E-04
- Koff wild-type (M-1s-1): 4E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None