1REW_AB_C

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  • Mutation(s) in PDB: KC88R, SC90T, KC92I, AC93P, QC94H, LC95Q, TC98D, AC74T, MC78L, KC79G, YC80L
  • Mutation(s) cleaned: KC57R,SC59T,KC61I,AC62P,QC63H,LC64Q,TC67D,AC43T,MC47L,KC48G,YC49L
  • Location: RIM,COR,RIM,COR,RIM,RIM,INT,INT,SUP,COR,RIM
  • Hold out type:
  • Hold out protein(s): 1REW_AB_C,2QJ9_AB_C,2QJA_AB_C,2QJB_AB_C,1KTZ_A_B
  • Affinity mutant: 1.1E-09
  • Affinity wild-typen: 7E-10
  • Reference: 18160401
  • Protein 1: Bone morphogenetic protein-2
  • Protein 2: BMPR-IA receptor
  • Method: SPR
  • Temperaute: 298(assumed) K
  • Kon mutatant (M-1s-1): 3E+05
  • Kon wild-type (M-1s-1): 3.4E+05
  • Koff mutatant (M-1s-1): 3.4E-04
  • Koff wild-type (M-1s-1): 2.4E-04
  • ΔH mutant (kcal mol-1)): None
  • ΔH wild-type (kcal mol-1)): None
  • ΔS mutant (cal mol-1 K-1): None
  • ΔS wild-type (cal mol-1 K-1): None