SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
2QJ9_AB_C
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- Mutation(s) in PDB:
AC74T,
MC78L,
KC79G,
YC80L
- Mutation(s) cleaned: AC43T,MC47L,KC48G,YC49L
- Location: INT,SUP,COR,RIM
- Hold out type:
- Hold out protein(s): 1REW_AB_C,2QJ9_AB_C,2QJA_AB_C,2QJB_AB_C,1KTZ_A_B
- Affinity mutant: 1.1E-09
- Affinity wild-typen: 2.4E-09
- Reference: 18160401
- Protein 1: Bone morphogenetic protein-2
- Protein 2: BMPR-IA receptor
- Method: SPR
- Temperaute: 298(assumed) K
- Kon mutatant (M-1s-1): 3E+05
- Kon wild-type (M-1s-1): 4E+05
- Koff mutatant (M-1s-1): 3.4E-04
- Koff wild-type (M-1s-1): 9.7E-04
- ΔH mutant (kcal mol-1)): None
- ΔH wild-type (kcal mol-1)): None
- ΔS mutant (cal mol-1 K-1): None
- ΔS wild-type (cal mol-1 K-1): None