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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut▲ | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2B2X_HL_A | VH50T,EH64K,QL28S... | VH50T,EH64K,QL28S... | SUP,SUR,RIM,RIM,RIM | AB/AG | AB/AG | 1.01E-08 | 1.46E-09 | AQC2 fab | Integrin alpha-1 | 298(assumed) | None | None | None | None | ELISA | ||||||
3NGB_HL_G | YH74S | YH75S | RIM | AB/AG | AB/AG | 1.01E-08 | 5.76E-09 | VRC01 fab | gp120 | 298 | 3.4E+04 | 3.83E+04 | 3.43E-04 | 2.2E-04 | None | None | None | None | SPR | ||
1CHO_EFG_I | GI32L | GI29L | SUP | Pr/PI | Pr/PI | 1.01E-10 | 5.26E-12 | Bovine alpha-chymotrypsin | Turkey ovomucoid third domain | 294 | None | None | None | None | FL | ||||||
1CHO_EFG_I | PI14K | PI11K | RIM | Pr/PI | Pr/PI | 1.01E-11 | 5.26E-12 | Bovine alpha-chymotrypsin | Turkey ovomucoid third domain | 294 | None | None | None | None | FL | ||||||
1PPF_E_I | PI14I | PI14I | RIM | Pr/PI | Pr/PI | 1.01E-11 | 1.64E-10 | Human leukocyte elastase | Turkey ovomucoid third domain | 294 | None | None | None | None | FL | ||||||
1S1Q_A_B | WA75A | WA73A | SUP | 1S1Q_A_B,2OOB_A_B... | 1.02E-03 | 6.35E-04 | Tumor susceptibility gene 101 protein | Ubiquitin | 293 | None | None | None | None | SPR | |||||||
1JTG_A_B | FB142A,YB143A,RA243A | FB142A,YB143A,RA217A | COR,COR,SUP | 1XXM_A_C,1S0W_A_C... | 1.02E-05 | 4.77E-09 | TEM-1 beta-lactamase | BLIP | 298 | None | None | None | None | SPR | |||||||
1AO7_ABC_DE | EA166A | EA166A | RIM | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.02E-05 | 8.8E-07 | HLA-A2 plus tax peptide | A6 TCR | 298 | 3.773585E+04 | 1.2E+05 | 3.65E-01 | 1E-01 | None | None | None | None | SPR | ||
3UIG_A_P | KA62A | KA58A | COR | 3UIG_A_P,3UII_A_P... | 1.02E-05 | 4.8E-06 | Survivin | T3 phosphorylated H3(1-15) peptide | 298 | -5.16 | -6.13 | 5.52 | 3.74 | ITC | |||||||
1KBH_A_B | YB98W,VB99A,LA17A | YB1172W,VB1173A,L... | SUP,INT,SUP | 1KBH_A_B | 1.02E-05 | 3.4E-08 | ACTR | CREB NCBD | 298(assumed) | None | None | None | None | SFFL |