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7085 records found

PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut▲ | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|

1ACB_E_I | LI45D | LI38D | COR | Pr/PI | Pr/PI | 1.61E-07 | 1.49E-12 | Bovine alpha-chymotrypsin | Eglin c | 294 | None | None | None | None | IASP | ||||||

1ACB_E_I | LI45E | LI38E | COR | Pr/PI | Pr/PI | 1.11E-07 | 1.49E-12 | Bovine alpha-chymotrypsin | Eglin c | 294 | None | None | None | None | IASP | ||||||

1SBN_E_I | RI45K | RI38K | COR | Pr/PI | Pr/PI | 3.2E-11 | 5.4E-11 | Subtilisin BPN | Eglin c | 298(assumed) | None | None | None | None | IASP | ||||||

1SIB_E_I | KI53R | KI46R | INT | Pr/PI | Pr/PI | 3.2E-11 | 1.1E-10 | Subtilisin BPN | Eglin c | 298(assumed) | None | None | None | None | IASP | ||||||

1TM1_E_I | YI61A | YI42A | COR | Pr/PI | Pr/PI | 7.92E-11 | 2E-12 | Subtilisin BPN | Chymotrypsin inhibitor 2 | 298 | 3.2E+06 | 5.6E+06 | 2.56E-04 | 1.06E-05 | None | None | None | None | SFFL | ||

1TM1_E_I | YI61G | YI42G | COR | Pr/PI | Pr/PI | 5.4E-09 | 2E-12 | Subtilisin BPN | Chymotrypsin inhibitor 2 | 298 | 3.5E+06 | 5.6E+06 | 1.88E-02 | 1.06E-05 | None | None | None | None | SFFL | ||

1TM1_E_I | RI65A | RI46A | INT | Pr/PI | Pr/PI | 3.62E-10 | 2E-12 | Subtilisin BPN | Chymotrypsin inhibitor 2 | 298 | 9.6E+05 | 3.1E+06 | 3.47E-04 | 6.1E-06 | None | None | None | None | SFFL | ||

1TM1_E_I | RI67A | RI48A | SUP | Pr/PI | Pr/PI | 2.78E-10 | 2E-12 | Subtilisin BPN | Chymotrypsin inhibitor 2 | 298 | 1.13E+06 | 3.1E+06 | 3.15E-04 | 6.1E-06 | None | None | None | None | SFFL | ||

1TM1_E_I | RI67C | RI48C | SUP | Pr/PI | Pr/PI | 4.71E-10 | 2E-12 | Subtilisin BPN | Chymotrypsin inhibitor 2 | 298 | 6.4E+05 | 3.1E+06 | 3.03E-04 | 6.1E-06 | None | None | None | None | SFFL | ||

1TM1_E_I | RI67A,RI65A | RI48A,RI46A | SUP,INT | Pr/PI | Pr/PI | 1.01E-08 | 2E-12 | Subtilisin BPN | Chymotrypsin inhibitor 2 | 298 | 7.8E+05 | 5.6E+06 | 7.92E-03 | 1.06E-05 | None | None | None | None | SFFL |