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RCSB
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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut▲ | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
2AK4_ABC_DE | TA69A | TA69A | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.05E-05 | 1.87E-05 | HLA-B35 plus LPEP viral peptide | SB27 TCR | 298 | 9.79E+04 | 6.56E+04 | 9.4E-02 | 1.2E-01 | None | None | None | None | SPR | ||
1AO7_ABC_DE | KD68H | KD66H | COR | TCR/pMHC | TCR/pMHC,1JCK_A_B | 1.05E-05 | 2.1E-06 | HLA-A2 plus tax peptide | A6 TCR | 298 | None | None | None | None | SPR | ||||||
3S9D_A_B | TB44A,LA15A | TB33A,LA8A | SUP,SUP | 3S9D_A_B,3SE3_B_C... | 1.05E-06 | 2.5E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | None | None | None | None | SP | |||||||
2WPT_A_B | NB75A | NB68A | SUP | 2WPT_A_B,2VLP_A_B... | 1.05E-07 | 1.3E-08 | Colicin E2 immunity protein | Colicin E9 DNase | 298 | 3.58E+08 | 6.9E+07 | 3.76E+01 | 9E-01 | None | None | None | None | RA | |||
3NCB_A_B | AA180H | AA167H | COR | 3MZG_A_B,3N06_A_B... | 1.05E-07 | 1.28E-06 | Prolactin | Prolactin receptor | 298 | 4.72E+04 | 5.15E+04 | 4.97E-03 | 6.58E-02 | None | None | None | None | SPR | |||
3NCC_A_B | AB188H | AB188H | COR | 3MZG_A_B,3N06_A_B... | 1.05E-07 | 3.6E-06 | Prolactin | Prolactin receptor | 298 | 4.72E+04 | 5.9E+04 | 4.97E-03 | 2.12E-01 | None | None | None | None | SPR | |||
1R0R_E_I | PI14S,AI15L,TI17K... | PI9S,AI10L,TI12K,... | RIM,COR,COR,COR | Pr/PI | Pr/PI | 1.05E-07 | 2.72E-11 | Subtilisin Carlsberg | Turkey ovomucoid third domain | 294 | None | None | None | None | IASP | ||||||
3SGB_E_I | AI15R,LI18R | AI9R,LI12R | COR,COR | Pr/PI | Pr/PI | 1.05E-07 | 1.79E-11 | Streptomyces griseus proteinase B | Turkey ovomucoid third domain | 294 | None | None | None | None | FL | ||||||
3S9D_A_B | HB76A,RA12A | HB65A,RA5A | COR,COR | 3S9D_A_B,3SE3_B_C... | 1.05E-07 | 2.5E-09 | Interferon alpha-2 | Interferon alpha/beta receptor 2 | 298(assumed) | None | None | None | None | SP | |||||||
3SGB_E_I | LI18M,YI20Q | LI12M,YI14Q | COR,COR | Pr/PI | Pr/PI | 1.05E-08 | 1.79E-11 | Streptomyces griseus proteinase B | Turkey ovomucoid third domain | 294 | None | None | None | None | FL |