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7085 records found
PDB Code | Mutation Pdb | Mutation Cleaned | Location | Hold Out Type | Hold Out Proteins | Affinity Mut | Affinity Wt | Ref. | Protein 1 | Protein 2 | T (ºK) | Kon Mut | Kon Wt | Koff Mut | Koff Wt | Dh Mut | Dh Wt | Ds Mut | Ds Wt | Method | |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1A22_A_B | YA42A,QA46A | YA42A,QA46A | COR,RIM | 1A22_A_B,1BP3_A_B | 4.6E-09 | 2.9E-09 | Human growth hormone | hGH binding protein | 298(assumed) | 1.8E+05 | 1.7E+05 | 8.5E-04 | 4.9E-04 | None | None | None | None | SPR | |||
1A22_A_B | FA25A,YA42A,QA46A | FA25A,YA42A,QA46A | COR,COR,RIM | 1A22_A_B,1BP3_A_B | 3.68E-09 | 2.6E-09 | Human growth hormone | hGH binding protein | 298(assumed) | -12.20 | -9.40 | -2.30 | 7.70 | ITC | |||||||
1A22_A_B | FA25A | FA25A | COR | 1A22_A_B,1BP3_A_B | 1.34E-09 | 2.6E-09 | Human growth hormone | hGH binding protein | 298(assumed) | -12.20 | -9.40 | -0.30 | 7.70 | ITC | |||||||
1A22_A_B | YA42A,QA46A | YA42A,QA46A | COR,RIM | 1A22_A_B,1BP3_A_B | 4.36E-09 | 2.6E-09 | Human growth hormone | hGH binding protein | 298(assumed) | -9.80 | -9.40 | 5.30 | 7.70 | ITC | |||||||
1A22_A_B | RB243A | RB11A | SUP | 1A22_A_B,1BP3_A_B | 3.95E-08 | 1E-09 | Human growth hormone | hGH binding protein | 298(assumed) | None | None | None | None | RA | |||||||
1A22_A_B | EB244A | EB12A | RIM | 1A22_A_B,1BP3_A_B | 2.01E-08 | 1E-09 | Human growth hormone | hGH binding protein | 298(assumed) | None | None | None | None | RA | |||||||
1A22_A_B | NB272A | NB31A | SUR | 1A22_A_B,1BP3_A_B | 1.35E-09 | 1E-09 | Human growth hormone | hGH binding protein | 298(assumed) | None | None | None | None | RA | |||||||
1A22_A_B | TB273A | TB32A | RIM | 1A22_A_B,1BP3_A_B | 1.14E-09 | 1E-09 | Human growth hormone | hGH binding protein | 298(assumed) | None | None | None | None | RA | |||||||
1A22_A_B | QB274A | QB33A | RIM | 1A22_A_B,1BP3_A_B | 1E-09 | 1E-09 | Human growth hormone | hGH binding protein | 298(assumed) | None | None | None | None | RA | |||||||
1A22_A_B | EB275A | EB34A | RIM | 1A22_A_B,1BP3_A_B | 8.13E-10 | 1E-09 | Human growth hormone | hGH binding protein | 298(assumed) | None | None | None | None | RA |