SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
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!=
<
>
<=
>=
starts with
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in
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>
<=
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in
not in
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!=
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<=
>=
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!=
<
>
<=
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starts with
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in
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!=
<
>
<=
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not in
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<
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<=
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<=
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starts with
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not in
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<
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<=
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not in
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starts with
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not in
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<
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<=
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starts with
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not in
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<
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<=
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starts with
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in
not in
=
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<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
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<
>
<=
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=
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<
>
<=
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starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
3SGB_E_I
KI13E
KI7E
COR
Pr/PI
Pr/PI
1.89E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
KI13H
KI7H
COR
Pr/PI
Pr/PI
9.09E-12
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
KI13F
KI7F
COR
Pr/PI
Pr/PI
5.26E-12
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
KI13R
KI7R
COR
Pr/PI
Pr/PI
5.56E-12
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
KI13Y
KI7Y
COR
Pr/PI
Pr/PI
6.67E-12
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
3SGB_E_I
KI13W
KI7W
COR
Pr/PI
Pr/PI
1.75E-11
1.79E-11
Streptomyces griseus proteinase B
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
GI32A
GI29A
SUP
Pr/PI
Pr/PI
8.33E-13
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
GI32S
GI29S
SUP
Pr/PI
Pr/PI
4.17E-12
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
GI32C
GI29C
SUP
Pr/PI
Pr/PI
3.85E-10
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
1CHO_EFG_I
GI32V
GI29V
SUP
Pr/PI
Pr/PI
1.72E-11
5.26E-12
Bovine alpha-chymotrypsin
Turkey ovomucoid third domain
294
None
None
None
None
FL
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