SKEMPI v2.0
Structural database of Kinetics and Energetics of Mutant Protein Interactions
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Records per page:
5
10
20
50
PDB Database to use:
PDBe
RCSB
PDBj
Mutations
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
=
!=
<
>
<=
>=
starts with
contains
in
not in
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!=
<
>
<=
>=
starts with
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in
not in
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!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
=
!=
<
>
<=
>=
starts with
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in
not in
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!=
<
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<=
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starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
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!=
<
>
<=
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starts with
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in
not in
=
!=
<
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<=
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starts with
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not in
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<=
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starts with
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not in
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<
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<=
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starts with
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not in
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<
>
<=
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starts with
contains
in
not in
=
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<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
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starts with
contains
in
not in
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
=
!=
<
>
<=
>=
starts with
contains
in
not in
7085 records found
PDB Code
Mutation Pdb
Mutation Cleaned
Location
Hold Out Type
Hold Out Proteins
Affinity Mut
Affinity Wt
Ref.
Protein 1
Protein 2
T (ºK)
Kon Mut
Kon Wt
Koff Mut
Koff Wt
Dh Mut
Dh Wt
Ds Mut
Ds Wt
Method
1PPF_E_I
GI32F
GI32F
COR
Pr/PI
Pr/PI
2E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
GI32R
GI32R
COR
Pr/PI
Pr/PI
5.88E-07
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
GI32Y
GI32Y
COR
Pr/PI
Pr/PI
1.25E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1PPF_E_I
GI32W
GI32W
COR
Pr/PI
Pr/PI
2.63E-09
1.64E-10
Human leukocyte elastase
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
GI32A
GI27A
SUP
Pr/PI
Pr/PI
2.63E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
GI32S
GI27S
SUP
Pr/PI
Pr/PI
1.37E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
GI32C
GI27C
SUP
Pr/PI
Pr/PI
3.23E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
GI32V
GI27V
SUP
Pr/PI
Pr/PI
7.69E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
GI32T
GI27T
SUP
Pr/PI
Pr/PI
5E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
1R0R_E_I
GI32P
GI27P
SUP
Pr/PI
Pr/PI
1.82E-10
2.94E-11
Subtilisin Carlsberg
Turkey ovomucoid third domain
294
None
None
None
None
FL
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